BioFocus DPI’s new structural biology offering significantly enhances our integrated medicinal chemistry, ADME/PK and biological screening services.  

• Structure based drug discovery - protein structure determination by X-ray crystallography as part of an integrated lead optimization program

• Access to Crystal Bank – a collection of available proteins for rapid X-ray structure analysis to determine client ligand/protein binding

• Preparation and crystallization of proteins and structure determination with bound client ligands

• Fragment-based screening using libraries designed with proprietary chemogenomic tools